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Young southerner Marco Russo moves to Northern Italy and finds work with the powerful Manzetti family He then proceeds to stir the pot between the Manzettis and their top rivals, the Belmondos

Five people receive an anonymous letter revealing a secret of theirs and inviting them to come stay at a mansion that houses a clinic run by a corrupt doctor who experiments on the brain of his comatose son

In Venice a detective is on the trail of a killer who commits a double murder a married couple then more grisly killings occur Sex, drugs, gore and perversions are ingredients of this sadistic and sleazy giallo